Function and Biology

Chondroitin sulfate/dermatan sulfate endolytic 4-O-sulfatase

Source organism: Vibrio sp. FC509
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 3.1.6.12: N-acetylgalactosamine-4-sulfatase

Reaction catalysed:
Hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate
Systematic name:
N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase
Alternative Name(s):
  • Acetylgalactosamine 4-sulfatase
  • Arylsulfatase B
  • Chondroitinase
  • Chondroitinsulfatase
  • N-acetylgalactosamine 4-sulfate sulfohydrolase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00884
Domain description: Sulfatase
Occurring in:
  1. Sulfatase N-terminal domain-containing protein
The deposited structure of PDB entry 6j66 contains 2 copies of Pfam domain PF00884 (Sulfatase) in Sulfatase N-terminal domain-containing protein. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR017850
Domain description: Alkaline-phosphatase-like, core domain superfamily
Occurring in:
  1. Sulfatase N-terminal domain-containing protein
IPR000917
Domain description: Sulfatase, N-terminal
Occurring in:
  1. Sulfatase N-terminal domain-containing protein
IPR006311
Domain description: Twin-arginine translocation pathway, signal sequence
Occurring in:
  1. Sulfatase N-terminal domain-containing protein