X-ray diffraction
1.95Å resolution

Chondroitin sulfate/dermatan sulfate endolytic 4-O-sulfatase


Function and Biology Details

Reaction catalysed:
Hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Sulfatase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 521 amino acids
Theoretical weight: 59.61 KDa
Source organism: Vibrio sp. FC509
Expression system: Escherichia coli BL21(DE3)
  • Canonical: A0A0C5AQI9 (Residues: 1-521; Coverage: 100%)
Sequence domains: Sulfatase

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 116.426Å b: 107.732Å c: 87.569Å
α: 90° β: 104.04° γ: 90°
R R work R free
0.182 0.18 0.214
Expression system: Escherichia coli BL21(DE3)