› 6j3n

X-ray diffraction
1.99Å resolution

RORgammat LBD complexed with Ursonic Acid and SRC2.2

Released:
DOI: 10.2210/pdb6j3n/pdb
PDB 6j3n coloured by chain and viewed from the front.
PDB 6j3n coloured by chain and viewed from the side.
PDB 6j3n coloured by chain and viewed from the top.
Source organisms:
Entry authors: Liu ZH, Huang J, Tang Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor ROR-gamma Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 28.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P51449 (Residues: 265-509; Coverage: 47%)
Gene names: NR1F3, RORC, RORG, RZRG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 1.02 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand B8F 1 x B8F
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P41212
Unit cell:
a: 61.93Å b: 61.93Å c: 155.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.233
Expression systems:
  • Escherichia coli BL21
  • Not provided

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