X-ray diffraction
1.99Å resolution

RORgammat LBD complexed with Ursonic Acid and SRC2.2

Entry authors: Liu ZH, Huang J, Tang Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor ROR-gamma Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 28.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P51449 (Residues: 265-509; Coverage: 47%)
Gene names: NR1F3, RORC, RORG, RZRG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 1.02 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P41212
Unit cell:
a: 61.93Å b: 61.93Å c: 155.87Å
α: 90° β: 90° γ: 90°
R R work R free
0.201 0.199 0.233
Expression systems:
  • Escherichia coli BL21
  • Not provided