X-ray diffraction
2.95Å resolution

Crystal structure of GalNAc-T7 with Mn2+

Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
N-acetylgalactosaminyltransferase 7 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 597 amino acids
Theoretical weight: 68.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: Q86SF2 (Residues: 61-657; Coverage: 91%)
Gene name: GALNT7
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P212121
Unit cell:
a: 137.695Å b: 158.233Å c: 251.87Å
α: 90° β: 90° γ: 90°
R R work R free
0.226 0.225 0.239
Expression system: Spodoptera frugiperda