X-ray diffraction
2.88Å resolution

Structure of mitochondrial CDP-DAG synthase Tam41 complexed with CTP, delta 74, F240A


Function and Biology Details

Reaction catalysed:
CTP + phosphatidate = diphosphate + CDP-diacylglycerol
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Phosphatidate cytidylyltransferase, mitochondrial Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 313 amino acids
Theoretical weight: 35.86 KDa
Source organism: Schizosaccharomyces pombe 972h-
Expression system: Escherichia coli
  • Canonical: O74339 (Residues: 28-319; Coverage: 74%)
Gene names: SPBC1A4.06c, tam41
Sequence domains: Phosphatidate cytidylyltransferase, mitochondrial

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Unit cell:
a: 55.266Å b: 187.418Å c: 186.57Å
α: 90° β: 90° γ: 90°
R R work R free
0.218 0.216 0.259
Expression system: Escherichia coli