6iec

X-ray diffraction
3.2Å resolution

Structure of RVFV Gn and human monoclonal antibody R17

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Glycoprotein N Chains: A, B, E, I
Molecule details ›
Chains: A, B, E, I
Length: 316 amino acids
Theoretical weight: 34.94 KDa
Source organism: Rift Valley fever virus
Expression system: Insect cell expression vector pTIE1
UniProt:
  • Canonical: P03518 (Residues: 154-469; Coverage: 27%)
Gene name: GP
R17 H chain Chains: C, F, H, J
Molecule details ›
Chains: C, F, H, J
Length: 115 amino acids
Theoretical weight: 12.61 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
R17 L chain Chains: D, G, K, L
Molecule details ›
Chains: D, G, K, L
Length: 111 amino acids
Theoretical weight: 11.87 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P62
Unit cell:
a: 198.009Å b: 198.009Å c: 164.467Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.243 0.241 0.281
Expression systems:
  • Insect cell expression vector pTIE1
  • Homo sapiens