6hsn

X-ray diffraction
1.55Å resolution

Crystal structure of the ternary complex of GephE-ADP-GABA(A) receptor derived peptide

Released:

Function and Biology Details

Reactions catalysed:
ATP + molybdopterin = diphosphate + adenylyl-molybdopterin
Adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP
Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Gephyrin Chain: A
Molecule details ›
Chain: A
Length: 419 amino acids
Theoretical weight: 45.65 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03555 (Residues: 350-768; Coverage: 55%)
Gene names: Gph, Gphn
Sequence domains:
Structure domains:
Gamma-aminobutyric acid receptor subunit alpha-3 Chains: D, E
Molecule details ›
Chains: D, E
Length: 10 amino acids
Theoretical weight: 1.11 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P20236 (Residues: 396-405; Coverage: 2%)
Gene names: Gabra-3, Gabra3

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-3
Spacegroup: I222
Unit cell:
a: 86.962Å b: 99.217Å c: 111.608Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.159 0.196
Expression systems:
  • Escherichia coli
  • Not provided