6hrz

X-ray diffraction
1.57Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 221 amino acids
Theoretical weight: 24.12 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O53623 (Residues: 1-201; Coverage: 100%)
Gene name: Rv0078
Sequence domains: Bacterial regulatory proteins, tetR family

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: C2
Unit cell:
a: 109.91Å b: 40.72Å c: 108.93Å
α: 90° β: 95.67° γ: 90°
R-values:
R R work R free
0.209 0.208 0.229
Expression system: Escherichia coli BL21