6hof

X-ray diffraction
1.8Å resolution

TRANSCRIPTIONAL REPRESSOR ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH BDM44852

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator EthR Chain: A
Molecule details ›
Chain: A
Length: 228 amino acids
Theoretical weight: 24.93 KDa
Source organism: Mycobacterium tuberculosis CDC1551
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P9WMC0 (Residues: 1-216; Coverage: 100%)
Gene names: MT3970, etaR, ethR
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P41212
Unit cell:
a: 121.849Å b: 121.849Å c: 33.766Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.209
Expression system: Escherichia coli BL21