6hn6

X-ray diffraction
2.71Å resolution

A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor RXR-ALPHA

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinoic acid receptor RXR-alpha Chain: A
Molecule details ›
Chain: A
Length: 282 amino acids
Theoretical weight: 31.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P19793 (Residues: 201-462; Coverage: 57%)
Gene names: NR2B1, RXRA
Sequence domains: Ligand-binding domain of nuclear hormone receptor

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P6322
Unit cell:
a: 110.8Å b: 110.8Å c: 109.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.173 0.231
Expression system: Escherichia coli BL21(DE3)