6hdb

X-ray diffraction
2.9Å resolution

Crystal structure of the potassium channel MtTMEM175 with zinc

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-122951 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Maltose/maltodextrin-binding periplasmic protein Chain: A
Molecule details ›
Chain: A
Length: 486 amino acids
Theoretical weight: 53.27 KDa
Source organism: Lama glama
Expression system: Escherichia coli MC1061
UniProt:
  • Canonical: P0AEX9 (Residues: 32-392; Coverage: 98%)
Gene names: JW3994, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Potassium channel Ftrac_2467 Chain: B
Molecule details ›
Chain: B
Length: 255 amino acids
Theoretical weight: 29.48 KDa
Source organism: Marivirga tractuosa DSM 4126
Expression system: Escherichia coli MC1061
UniProt:
  • Canonical: E4TN31 (Residues: 2-247; Coverage: 100%)
Gene name: Ftrac_2467
Sequence domains: Endosomal/lysosomal potassium channel TMEM175

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P4212
Unit cell:
a: 131.92Å b: 131.92Å c: 132.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.276 0.275 0.286
Expression system: Escherichia coli MC1061