› 6h4l

X-ray diffraction
1.6Å resolution

Structure of Titin M4 trigonal form

Released:
DOI: 10.2210/pdb6h4l/pdb
PDB entry 6h4l coloured by chain, front view.
PDB entry 6h4l coloured by chain, side view.
PDB entry 6h4l coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural diversity in the atomic resolution 3D fingerprint of the titin M-band segment.
Chatziefthimiou SD, Hornburg P, Sauer F, Mueller S, Ugurlar D, Xu ER, Wilmanns M
PLoS One 14 e0226693 (2019)
PMID: 31856237

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186809 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Titin Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WZ42 (Residues: 33294-33395; Coverage: 0%)
Gene name: TTN
Sequence domains: Immunoglobulin I-set domain

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P3221
Unit cell:
a: 84.847Å b: 84.847Å c: 49.177Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.208 0.221
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 mention without citation

Structural diversity in the atomic resolution 3D fingerprint of the titin M-band segment.
Chatziefthimiou et al. (2019)