› 6h2t

X-ray diffraction
1.67Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PBPb domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 288 amino acids
Theoretical weight: 31.41 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P96257 (Residues: 41-328; Coverage: 95%)
Gene names: Rv0411c, glnH
Sequence domains: Bacterial extracellular solute-binding proteins, family 3

Ligands and Environments

1 bound ligand:
Ligand GLU 1 x GLU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 47.76Å b: 81.07Å c: 87.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.163 0.162 0.179
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G.
Kidwai et al. (2019)
1 more