6h2a

X-ray diffraction
2.54Å resolution

Structure of S70A BlaC from Mycobacterium tuberculosis obtained from crystals produced in the presence of DTT

Released:
Source organism: Mycobacterium tuberculosis
Entry authors: Tassoni R, Pannu NS, Ubbink M

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Beta-lactamase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 274 amino acids
Theoretical weight: 29.46 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
Structure domains: DD-peptidase/beta-lactamase superfamily
Possible protein degradation product Chain: H
Molecule details ›
Chain: H
Length: 6 amino acids
Theoretical weight: 360 Da
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P43212
Unit cell:
a: 108.864Å b: 108.864Å c: 260.577Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.228 0.256
Expression system: Escherichia coli BL21(DE3)