PDBe 6gwz

X-ray diffraction
1.65Å resolution

Blood group synthase AAGlyB in its apo form cryoprotected with PEG 3350

Released:
Source organism: Homo sapiens
Entry authors: Rocha J, Royant A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) Chain: A
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 34.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: F0X360 (Residues: 54-344; Coverage: 85%)
Gene name: ABO

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2221
Unit cell:
a: 52.879Å b: 149.625Å c: 79.644Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.168 0.208
Expression system: Escherichia coli