6gvk

X-ray diffraction
1.55Å resolution

Second pair of Fibronectin type III domains of integrin beta4 (T1663R mutant) bound to the bullous pemphigoid antigen BP230 (BPAG1e)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin beta-4 Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 23.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P16144 (Residues: 1527-1736; Coverage: 12%)
Gene name: ITGB4
Sequence domains: Fibronectin type III domain
Dystonin Chain: B
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: C2
Unit cell:
a: 105.58Å b: 59.52Å c: 42.4Å
α: 90° β: 113.5° γ: 90°
R-values:
R R work R free
0.196 0.195 0.21
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided