› 6gvb

X-ray diffraction
1.8Å resolution

Crystal structure of Cutibacterium acnes exo-beta-1,4-mannosidase

Released:
DOI: 10.2210/pdb6gvb/pdb
PDB entry 6gvb coloured by chain, front view.
PDB entry 6gvb coloured by chain, side view.
PDB entry 6gvb coloured by chain, top view.
Source organism: Cutibacterium acnes
Primary publication:
Structural and biochemical characterization of the Cutibacterium acnes exo-β-1,4-mannosidase that targets the N-glycan core of host glycoproteins.
Reichenbach T, Kalyani D, Gandini R, Svartström O, Aspeborg H, Divne C
PLoS One 13 e0204703 (2018)
PMID: 30261037

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166783 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
exo-beta-1,4-mannosidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 416 amino acids
Theoretical weight: 46.73 KDa
Source organism: Cutibacterium acnes
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

1 bound ligand:
Ligand MPO 12 x MPO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P21
Unit cell:
a: 84.18Å b: 104.37Å c: 112.75Å
α: 90° β: 90.27° γ: 90°
R-values:
R R work R free
0.195 0.195 0.226
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Cutibacterium acnes as an Opportunistic Pathogen: An Update of Its Virulence-Associated Factors.
Mayslich et al. (2021)
3 other articles

2 mentions without citation

Structural and biochemical characterization of the Cutibacterium acnes exo-β-1,4-mannosidase that targets the N-glycan core of host glycoproteins.
Reichenbach et al. (2018)
1 more