X-ray diffraction
1.72Å resolution

Crystal structure of a FimH*DsG complex from E.coli F18 with bound dimannoside Man(alpha1-3)Man in space group P21


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
FimH protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 279 amino acids
Theoretical weight: 29.05 KDa
Source organism: Escherichia coli F18+
Expression system: Escherichia coli
  • Canonical: A0A0R4I961 (Residues: 1-279; Coverage: 100%)
Gene names: ECP_4655, fimh
Sequence domains:
FimG protein Chains: B, D
Molecule details ›
Chains: B, D
Length: 14 amino acids
Theoretical weight: 1.42 KDa
Source organism: Escherichia coli 536
Expression system: Not provided
  • Canonical: A0A140UH97 (Residues: 1-14; Coverage: 100%)
Gene name: ECP_4654

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 44.637Å b: 115.112Å c: 63.158Å
α: 90° β: 107.58° γ: 90°
R R work R free
0.18 0.179 0.203
Expression systems:
  • Escherichia coli
  • Not provided