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METTL16 MTase domain (crystal form 2)

X-ray diffraction
2.45Å resolution
PDB entry 6gt5 coloured by chain, front view.
PDB entry 6gt5 coloured by chain, side view.
PDB entry 6gt5 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: RNA N6-adenosine-methyltransferase METTL16
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Multimeric state: monomeric
Accessible surface area: 12254.6 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-183225
Assembly 2
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Assembly Name: RNA N6-adenosine-methyltransferase METTL16
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Multimeric state: monomeric
Accessible surface area: 12182.12 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-183225

Macromolecules

RNA N6-adenosine-methyltransferase METTL16
Chains: A, B
Length: 291 amino acids
Theoretical weight: 33.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q86W50 (Residues: 1-291; Coverage: 52%)
Gene names: METT10D, METTL16
Pfam: RNA methyltransferase
InterPro:
RNA N6-adenosine-methyltransferase METTL16 in PDB entry 6gt5, assembly 1, front view.
RNA N6-adenosine-methyltransferase METTL16 in PDB entry 6gt5, assembly 1, side view.
RNA N6-adenosine-methyltransferase METTL16 in PDB entry 6gt5, assembly 1, top view.
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