› 6grq

X-ray diffraction
3.3Å resolution

Paired immunoglobulin-like receptor B (PirB) or Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) full extracellular domain

Released:
DOI: 10.2210/pdb6grq/pdb
PDB 6grq coloured by chain and viewed from the front.
PDB 6grq coloured by chain and viewed from the side.
PDB 6grq coloured by chain and viewed from the top.
Source organism: Mus musculus
Primary publication:
Structure and flexibility of the extracellular region of the PirB receptor.
Vlieg HC, Huizinga EG, Janssen BJC
J Biol Chem 294 4634-4643 (2019)
PMID: 30674550

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 606 amino acids
Theoretical weight: 67.46 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8K4V6 (Residues: 25-619; Coverage: 88%)
Gene names: Lilrb3, Pirb
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P4122
Unit cell:
a: 106.375Å b: 106.375Å c: 217.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.248 0.295
Expression system: Homo sapiens

Quick links

Citations

1 review citation

Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer.
Deng et al. (2021)
1 other article