X-ray diffraction
1.65Å resolution

Crystal Structure Of Sea Bream Transthyretin in complex with Perfluorooctanoic acid (PFOA). Crystallized in PEG


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Transthyretin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 135 amino acids
Theoretical weight: 14.46 KDa
Source organism: Sparus aurata
Expression system: Escherichia coli
  • Canonical: Q9PTT3 (Residues: 20-149; Coverage: 99%)
Sequence domains: HIUase/Transthyretin family

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 72.408Å b: 76.203Å c: 107.103Å
α: 90° β: 90° γ: 90°
R R work R free
0.161 0.159 0.193
Expression system: Escherichia coli