Function and Biology

Solution structure of FUS-RRM bound to stem-loop RNA

Source organism: Homo sapiens
Biochemical function: RNA binding
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00076
Domain description: RNA recognition motif
Occurring in:
  1. RNA-binding protein FUS
The deposited structure of PDB entry 6gbm contains 1 copy of Pfam domain PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) in RNA-binding protein FUS. Showing 1 copy in chain A [auth B].

InterPro InterPro annotations
IPR000504
Domain description: RNA recognition motif domain
Occurring in:
  1. RNA-binding protein FUS
IPR012677
Domain description: Nucleotide-binding alpha-beta plait domain superfamily
Occurring in:
  1. RNA-binding protein FUS
IPR035979
Domain description: RNA-binding domain superfamily
Occurring in:
  1. RNA-binding protein FUS
IPR034870
Domain description: TAF15/EWS/TLS family
Occurring in:
  1. RNA-binding protein FUS

Structure domain

CATH CATH domain
3.30.70.330
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Alpha-Beta Plaits
Occurring in:
  1. RNA-binding protein FUS
The deposited structure of PDB entry 6gbm contains 1 copy of CATH domain 3.30.70.330 (Alpha-Beta Plaits) in RNA-binding protein FUS. Showing 1 copy in chain A [auth B].