› 6g6u

X-ray diffraction
2.74Å resolution

The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 2.7 Angstrom resolution

Released:
DOI: 10.2210/pdb6g6u/pdb
PDB 6g6u coloured by chain and viewed from the front.
PDB 6g6u coloured by chain and viewed from the side.
PDB 6g6u coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Razeto A, Gribbon P, Loew C

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-dependent anion-selective channel protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 291 amino acids
Theoretical weight: 31.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P21796 (Residues: 1-283; Coverage: 100%)
Gene names: VDAC, VDAC1
Sequence domains: Eukaryotic porin
Structure domains: Porin

Ligands and Environments

2 bound ligands:
Ligand MC3 3 x MC3
Ligand NO3 2 x NO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P21
Unit cell:
a: 51.4Å b: 58.15Å c: 122.72Å
α: 90° β: 94.03° γ: 90°
R-values:
R R work R free
0.257 0.256 0.287
Expression system: Escherichia coli BL21(DE3)

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