6g6u

X-ray diffraction
2.74Å resolution

The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 2.7 Angstrom resolution

Released:
Source organism: Homo sapiens
Entry authors: Razeto A, Gribbon P, Loew C

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-dependent anion-selective channel protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 291 amino acids
Theoretical weight: 31.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P21796 (Residues: 1-283; Coverage: 100%)
Gene names: VDAC, VDAC1
Sequence domains: Eukaryotic porin
Structure domains: Porin

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P21
Unit cell:
a: 51.4Å b: 58.15Å c: 122.72Å
α: 90° β: 94.03° γ: 90°
R-values:
R R work R free
0.257 0.256 0.287
Expression system: Escherichia coli BL21(DE3)