Function and Biology

Crystal structure of Smad5-MH1 bound to the GGCGC site.

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of DNA-templated transcription
Cellular component: transcription regulator complex

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF03165
Domain description: MH1 domain
Occurring in:
  1. Mothers against decapentaplegic homolog 5
The deposited structure of PDB entry 6fzs contains 2 copies of Pfam domain PF03165 (MH1 domain) in Mothers against decapentaplegic homolog 5. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR003619
Domain description: MAD homology 1, Dwarfin-type
Occurring in:
  1. Mothers against decapentaplegic homolog 5
IPR036578
Domain description: SMAD MH1 domain superfamily
Occurring in:
  1. Mothers against decapentaplegic homolog 5
IPR013019
Domain description: MAD homology, MH1
Occurring in:
  1. Mothers against decapentaplegic homolog 5
IPR013790
Domain description: Dwarfin
Occurring in:
  1. Mothers against decapentaplegic homolog 5