› 6fxi

X-ray diffraction
2.6Å resolution

Human PARP10 (ARTD10), catalytic fragment in complex with 3-aminobenzamide and citrate

Released:
DOI: 10.2210/pdb6fxi/pdb
PDB entry 6fxi coloured by chain, front view.
PDB entry 6fxi coloured by chain, side view.
PDB entry 6fxi coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Karlberg T, Thorsell AG, Schuler H

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176098 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein mono-ADP-ribosyltransferase PARP10 Chains: A, B
Molecule details ›
Chains: A, B
Length: 191 amino acids
Theoretical weight: 21.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q53GL7 (Residues: 819-1007; Coverage: 18%)
Gene name: PARP10
Sequence domains: Poly(ADP-ribose) polymerase catalytic domain
Structure domains: Phosphoenolpyruvate Carboxykinase; domain 3

Ligands and Environments

3 bound ligands:
Ligand 3AB 2 x 3AB
Ligand CIT 2 x CIT
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 51.6Å b: 86.6Å c: 57.46Å
α: 90° β: 104.98° γ: 90°
R-values:
R R work R free
0.212 0.21 0.245
Expression system: Escherichia coli

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