6fw2

X-ray diffraction
1.78Å resolution

Crystal Structure of human mARC1

Released:

Function and Biology Details

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endolysin; Mitochondrial amidoxime-reducing component 1 Chain: A
Molecule details ›
Chain: A
Length: 459 amino acids
Theoretical weight: 51.85 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: Q5VT66 (Residues: 53-128, 131-336; Coverage: 84%)
  • Canonical: P00720 (Residues: 1-159; Coverage: 97%)
Gene names: E, MARC1, MOSC1, MTARC1
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: P212121
Unit cell:
a: 61.133Å b: 74.818Å c: 110.726Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.208
Expression system: Escherichia coli