Function and Biology

Crystal structure of Ssp DnaB Mini-Intein variant M86

Source organism: Synechocystis sp. PCC 6803 substr. Kazusa
Biochemical function: not assigned
Biological process: intein-mediated protein splicing
Cellular component: not assigned

EC 3.6.4.12: DNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (DNA helix unwinding)
Alternative Name(s):
  • 3' to 5' DNA helicase
  • 3'-5' DNA helicase
  • 3'-5' PfDH
  • 5' to 3' DNA helicase
  • AvDH1
  • BACH1 helicase
  • BLM protein
  • BRCA1-associated C-terminal helicase
  • BcMCM
  • CeWRN-1
  • DNA helicase 120
  • DNA helicase A
  • DNA helicase E
  • DNA helicase II
  • DNA helicase III
  • DNA helicase RECQL5'
  • DNA helicase VI
  • Dbp9p
  • DmRECQ5
  • DnaB
  • DnaB helicase E1
  • HHcsA
  • HPif1
  • Hel E
  • Helicase DnaB
  • Helicase HDH IV
  • Helicase domain of bacteriophage T7 gene 4 protein helicase
  • Hmi1p
  • MCM helicase
  • MCM protein
  • MER3 helicase
  • MER3 protein
  • MPH1
  • PDH120
  • PIF1
  • PcrA
  • PcrA helicase
  • PfDH A
  • Pfh1p
  • UvrD

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF03796
Domain description: DnaB-like helicase C terminal domain
Occurring in:
  1. Ssp dnaB intein

PF14890
Domain description: Intein splicing domain
Occurring in:
  1. Ssp dnaB intein

InterPro InterPro annotations
IPR030934
Domain description: Intein C-terminal splicing region
Occurring in:
  1. Ssp dnaB intein
IPR006141
Domain description: Intein N-terminal splicing region
Occurring in:
  1. Ssp dnaB intein
IPR003586
Domain description: Hint domain C-terminal
Occurring in:
  1. Ssp dnaB intein
IPR036844
Domain description: Hint domain superfamily
Occurring in:
  1. Ssp dnaB intein
IPR003587
Domain description: Hint domain N-terminal
Occurring in:
  1. Ssp dnaB intein

Structure domain

CATH CATH domain
2.170.16.10
Class: Mainly Beta
Architecture: Beta Complex
Topology: Endonuclease - Pi-scei; Chain A, domain 1
Homology: Hedgehog/Intein (Hint) domain
Occurring in:
  1. Ssp dnaB intein
The deposited structure of PDB entry 6frh contains 2 copies of CATH domain 2.170.16.10 (Endonuclease - Pi-scei; Chain A, domain 1) in Ssp dnaB intein. Showing 1 copy in chain A.