› 6fk2

X-ray diffraction
1.01Å resolution

Galectin-3 carbohydrate recognition domain in complex with lactitol

Released:
DOI: 10.2210/pdb6fk2/pdb
PDB 6fk2 coloured by chain and viewed from the front.
PDB 6fk2 coloured by chain and viewed from the side.
PDB 6fk2 coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Doran SMC, Faba Rodriguez R, Hemmings AM

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-3 Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17931 (Residues: 113-250; Coverage: 55%)
Gene names: LGALS3, MAC2
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: SOR, GAL
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 37.295Å b: 57.631Å c: 62.604Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.134 0.134 0.141
Expression system: Escherichia coli BL21(DE3)

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