6fk2

X-ray diffraction
1.01Å resolution

Galectin-3 carbohydrate recognition domain in complex with lactitol

Released:
Source organism: Homo sapiens
Entry authors: Doran SMC, Faba Rodriguez R, Hemmings AM

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-3 Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17931 (Residues: 113-250; Coverage: 55%)
Gene names: LGALS3, MAC2
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: SOR, GAL
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 37.295Å b: 57.631Å c: 62.604Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.134 0.134 0.141
Expression system: Escherichia coli BL21(DE3)