6fg1

X-ray diffraction
2.03Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
HEAVY CHAIN OF FAB NAA32 Chain: A
Molecule details ›
Chain: A
Length: 241 amino acids
Theoretical weight: 26.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
LIGHT CHAIN OF FAB NAA32 Chain: D
Molecule details ›
Chain: D
Length: 215 amino acids
Theoretical weight: 23.37 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
HEAVY CHAIN OF FAB NATALIZUMAB Chain: H
Molecule details ›
Chain: H
Length: 234 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
LIGHT CHAIN OF FAB NATALIZUMAB Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 23.58 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P4212
Unit cell:
a: 189.101Å b: 189.101Å c: 87.259Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.267 0.266 0.285
Expression system: Homo sapiens