6fdn

X-ray diffraction
2.9Å resolution

Rio2 structure

Released:
Source organism: Homo sapiens
Primary publication:
In vitro dimerization of human RIO2 kinase.
RNA Biol 1-10 (2019)
PMID: 31390939

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase RIO2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 320 amino acids
Theoretical weight: 37.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q9BVS4 (Residues: 1-320; Coverage: 58%)
Gene names: RIO2, RIOK2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 58.592Å b: 86.405Å c: 121.544Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.226 0.267
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'