› 6fdd

X-ray diffraction
1.75Å resolution

Crystal Structure of the HHD2 Domain of Whirlin

Released:
DOI: 10.2210/pdb6fdd/pdb
PDB 6fdd coloured by chain and viewed from the front.
PDB 6fdd coloured by chain and viewed from the side.
PDB 6fdd coloured by chain and viewed from the top.
Source organism: Mus musculus
Primary publication:
Structural plasticity of the HHD2 domain of whirlin.
Delhommel F, Cordier F, Saul F, Chataigner L, Haouz A, Wolff N
FEBS J. (2018)
PMID: 30053338

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Whirlin Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 85 amino acids
Theoretical weight: 9.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q80VW5 (Residues: 420-499; Coverage: 9%)
  • Best match: Q80VW5-6 (Residues: 1-57)
Gene names: Dfnb31, Kiaa1526, Whrn

Ligands and Environments

1 bound ligand:
Ligand SO4 7 x SO4
1 modified residue:
Ligand MSE 30 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2
Unit cell:
a: 118.58Å b: 74.91Å c: 63.84Å
α: 90° β: 106.38° γ: 90°
R-values:
R R work R free
0.188 0.187 0.21
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

αα-Hub domains and intrinsically disordered proteins: A decisive combo.
Bugge et al. (2021)

6 mentions without citation

Compatibilized Immiscible Polymer Blends for Gas Separations.
Panapitiya et al. (2016)
5 more