X-ray diffraction
1.66Å resolution

Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine

Source organism: Escherichia coli
Entry authors: Stiel AC, Shanmugaratnam S, Hocker B

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Trp operon repressor Chains: A, C
Molecule details ›
Chains: A, C
Length: 103 amino acids
Theoretical weight: 11.84 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21
  • Canonical: P0A881 (Residues: 4-106; Coverage: 95%)
Gene names: JW4356, b4393, rtrY, trpR
Sequence domains: Trp repressor protein
Structure domains: TrpR-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 35.349Å b: 55.548Å c: 66.992Å
α: 90° β: 98.82° γ: 90°
R R work R free
0.187 0.185 0.226
Expression system: Escherichia coli BL21