6f4v

X-ray diffraction
1.8Å resolution

Crystal structure of cleaved Kallistatin complexed with heparin at 1.8 Angstrom resolution

Released:
Source organism: Homo sapiens
Entry authors: Zhou A, Wei Z

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Kallistatin Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 39.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29622 (Residues: 48-387; Coverage: 84%)
Gene names: KST, PI4, SERPINA4
Structure domains:
Kallistatin Chain: G
Molecule details ›
Chain: G
Length: 40 amino acids
Theoretical weight: 4.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29622 (Residues: 388-427; Coverage: 10%)
Gene names: KST, PI4, SERPINA4

Ligands and Environments

Carbohydrate polymer : NEW Components: Z9L, Z9K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P61
Unit cell:
a: 113.77Å b: 113.77Å c: 76.561Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.173 0.172 0.196
Expression system: Escherichia coli