6f4u

X-ray diffraction
1.9Å resolution

Crystal structure of reactive loop cleaved kallistatin at 1.9 angstrom resolution

Released:
Source organism: Homo sapiens
Entry authors: Zhou A, Wei Z, Lin F

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kallistatin Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 39.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29622 (Residues: 48-387; Coverage: 84%)
Gene names: KST, PI4, SERPINA4
Structure domains:
Kallistatin Chain: D
Molecule details ›
Chain: D
Length: 40 amino acids
Theoretical weight: 4.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29622 (Residues: 388-427; Coverage: 10%)
Gene names: KST, PI4, SERPINA4

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P61
Unit cell:
a: 113.51Å b: 113.51Å c: 76.172Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.195
Expression system: Escherichia coli BL21(DE3)