6f3t

X-ray diffraction
2.5Å resolution

Crystal structure of the human TAF5-TAF6-TAF9 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Transcription initiation factor TFIID subunit 5 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 608 amino acids
Theoretical weight: 68.95 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: Q15542 (Residues: 194-800; Coverage: 76%)
Gene names: TAF2D, TAF5
Sequence domains:
Transcription initiation factor TFIID subunit 6 Chains: E, G, I, K
Molecule details ›
Chains: E, G, I, K
Length: 94 amino acids
Theoretical weight: 10.89 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P49848 (Residues: 5-92; Coverage: 13%)
Gene names: TAF2E, TAF6, TAFII70
Sequence domains: TATA box binding protein associated factor (TAF)
Transcription initiation factor TFIID subunit 9 Chains: F, H, J, L
Molecule details ›
Chains: F, H, J, L
Length: 116 amino acids
Theoretical weight: 13.33 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: Q16594 (Residues: 5-120; Coverage: 44%)
Gene names: TAF2G, TAF9, TAFII31

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: I23
Unit cell:
a: 339.05Å b: 339.05Å c: 339.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.197 0.22
Expression system: unidentified baculovirus