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Structure of yeast Sec14p with a picolinamide compound

Source organism: Saccharomyces cerevisiae S288C
Biochemical function: phosphatidylinositol transfer activity
Biological process: negative regulation of phosphatidylcholine biosynthetic process
Cellular component: membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00650
Domain description: CRAL/TRIO domain
Occurring in:
  1. SEC14 cytosolic factor
The deposited structure of PDB entry 6f0e contains 1 copy of Pfam domain PF00650 (CRAL/TRIO domain) in SEC14 cytosolic factor. Showing 1 copy in chain A.

PF03765
Domain description: CRAL/TRIO, N-terminal domain
Occurring in:
  1. SEC14 cytosolic factor
The deposited structure of PDB entry 6f0e contains 1 copy of Pfam domain PF03765 (CRAL/TRIO, N-terminal domain) in SEC14 cytosolic factor. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001251
Domain description: CRAL-TRIO lipid binding domain
Occurring in:
  1. SEC14 cytosolic factor
IPR036865
Domain description: CRAL-TRIO lipid binding domain superfamily
Occurring in:
  1. SEC14 cytosolic factor
IPR011074
Domain description: CRAL/TRIO, N-terminal domain
Occurring in:
  1. SEC14 cytosolic factor
IPR036273
Domain description: CRAL/TRIO, N-terminal domain superfamily
Occurring in:
  1. SEC14 cytosolic factor

Structure domains

CATH CATH domains
3.40.525.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Phosphatidylinositol Transfer Protein Sec14p
Homology: CRAL-TRIO lipid binding domain
Occurring in:
  1. SEC14 cytosolic factor
The deposited structure of PDB entry 6f0e contains 1 copy of CATH domain 3.40.525.10 (Phosphatidylinositol Transfer Protein Sec14p) in SEC14 cytosolic factor. Showing 1 copy in chain A.
1.10.8.20
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helicase, Ruva Protein; domain 3
Homology: N-terminal domain of phosphatidylinositol transfer protein sec14p
Occurring in:
  1. SEC14 cytosolic factor
The deposited structure of PDB entry 6f0e contains 1 copy of CATH domain 1.10.8.20 (Helicase, Ruva Protein; domain 3) in SEC14 cytosolic factor. Showing 1 copy in chain A.

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