6ew3

X-ray diffraction
2.14Å resolution

Crystal structure of the metallo-beta-lactamase VIM-2 with ML302F

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-112316 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallo-beta-lactamase type 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 232 amino acids
Theoretical weight: 24.77 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: D1MEN9 (Residues: 32-263; Coverage: 94%)
Gene name: blaVIM-2
Sequence domains: Metallo-beta-lactamase superfamily
Structure domains: Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 102.48Å b: 78.91Å c: 67.46Å
α: 90° β: 130.48° γ: 90°
R-values:
R R work R free
0.171 0.169 0.21
Expression system: Escherichia coli