X-ray diffraction
2.69Å resolution

Crystal structure of Platynereis dumerilii RAR ligand-binding domain in complex with all-trans retinoic acid

Source organism: Platynereis dumerilii
Entry authors: Handberg-Thorsager M, Gutierrez-Mazariegos J, Arold ST, Nadendla EK, Bertucci PY, Germain P, Tomancak P, Pierzchalski K, Jones JW, Albalat R, Kane MA, Bourguet W, Laudet V, Arendt D, Schubert M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
NR LBD domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 241 amino acids
Theoretical weight: 27.46 KDa
Source organism: Platynereis dumerilii
Expression system: Escherichia coli BL21(DE3)
  • Canonical: A0A384E144 (Residues: 1-241; Coverage: 100%)
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 187.41Å b: 68.15Å c: 95.08Å
α: 90° β: 100.75° γ: 90°
R R work R free
0.257 0.255 0.3
Expression system: Escherichia coli BL21(DE3)