6erh

X-ray diffraction
2.8Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct DNA molecules
Macromolecules (5 distinct):
X-ray repair cross-complementing protein 6 Chains: A, C
Molecule details ›
Chains: A, C
Length: 544 amino acids
Theoretical weight: 62.63 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P12956 (Residues: 1-544; Coverage: 89%)
Gene names: G22P1, XRCC6
Sequence domains:
Structure domains:
X-ray repair cross-complementing protein 5 Chains: B, D
Molecule details ›
Chains: B, D
Length: 572 amino acids
Theoretical weight: 65.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P13010 (Residues: 2-555; Coverage: 76%)
Gene names: G22P2, XRCC5
Sequence domains:
Non-homologous end-joining factor 1 Chains: M, T
Molecule details ›
Chains: M, T
Length: 19 amino acids
Theoretical weight: 2.27 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9H9Q4 (Residues: 281-299; Coverage: 6%)
Gene names: NHEJ1, XLF
DNA (34-MER) Chains: F, O
Molecule details ›
Chains: F, O
Length: 34 nucleotides
Theoretical weight: 10.33 KDa
DNA (21-MER) Chains: K, R
Molecule details ›
Chains: K, R
Length: 21 nucleotides
Theoretical weight: 6.51 KDa

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 2
Spacegroup: P21
Unit cell:
a: 111.847Å b: 118.925Å c: 128.219Å
α: 90° β: 93.11° γ: 90°
R-values:
R R work R free
0.226 0.225 0.252
Expression systems:
  • Spodoptera frugiperda
  • Not provided