Structure analysis

DPP8 - SLRFLYEG, space group 20

X-ray diffraction
2.4Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 64220.38 Å2
Buried surface area: 10604.96 Å2
Dissociation area: 2,326.4 Å2
Dissociation energy (ΔGdiss): 5.32 kcal/mol
Dissociation entropy (TΔSdiss): 16.1 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-159023
Assembly 2
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Multimeric state: hetero tetramer
Accessible surface area: 63029.2 Å2
Buried surface area: 10072.56 Å2
Dissociation area: 2,343.74 Å2
Dissociation energy (ΔGdiss): 5.89 kcal/mol
Dissociation entropy (TΔSdiss): 16.09 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-159023

Macromolecules

Chains: A, B, C
Length: 898 amino acids
Theoretical weight: 103.56 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q6V1X1 (Residues: 1-898; Coverage: 100%)
Gene names: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
Pfam:
InterPro:

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Chains: D, E, F
Length: 8 amino acids
Theoretical weight: 985 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P63165 (Residues: 61-68; Coverage: 8%)
Gene names: OK/SW-cl.43, SMT3C, SMT3H3, SUMO1, UBL1

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