› 6eoh

X-ray diffraction
1.85Å resolution

Reductive Aminase from Aspergillus terreus in complex with NADPH and ethyl levulinate

Released:
DOI: 10.2210/pdb6eoh/pdb
PDB entry 6eoh coloured by chain, front view.
PDB entry 6eoh coloured by chain, side view.
PDB entry 6eoh coloured by chain, top view.
Source organism: Aspergillus terreus
Primary publication:
A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases
Sharma M, Mangas-Sanchez J, Turner NJ, Grogan G
ACS Catalysis (2018)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170873 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Reductive Aminase Chains: A, B
Molecule details ›
Chains: A, B
Length: 298 amino acids
Theoretical weight: 30.76 KDa
Source organism: Aspergillus terreus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0CCT3 (Residues: 1-298; Coverage: 100%)
Gene name: ATEG_08501
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NAP 2 x NAP
Ligand BKQ 1 x BKQ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 38.95Å b: 162.954Å c: 48.155Å
α: 90° β: 106.84° γ: 90°
R-values:
R R work R free
0.219 0.217 0.255
Expression system: Escherichia coli

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