› 6eoa

X-ray diffraction
2.18Å resolution

Crystal Structure of HAL3 from Cryptococcus neoformans

Released:
DOI: 10.2210/pdb6eoa/pdb
PDB entry 6eoa coloured by chain, front view.
PDB entry 6eoa coloured by chain, side view.
PDB entry 6eoa coloured by chain, top view.
Source organism: Cryptococcus neoformans
Primary publication:
Characterization of the atypical Ppz/Hal3 phosphatase system from the pathogenic fungus Cryptococcus neoformans.
Zhang C, García-Rodas R, Molero C, de Oliveira HC, Tabernero L, Reverter D, Zaragoza O, Ariño J
Mol Microbiol 111 898-917 (2019)
PMID: 30536975

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125413 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Flavoprotein domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 325 amino acids
Theoretical weight: 35.1 KDa
Source organism: Cryptococcus neoformans
Expression system: Escherichia coli
UniProt:
  • Canonical: J9VGI2 (Residues: 1-325; Coverage: 100%)
Gene name: CNAG_07348
Sequence domains: Flavoprotein

Ligands and Environments

1 bound ligand:
Ligand FMN 1 x FMN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: R32
Unit cell:
a: 88.194Å b: 88.194Å c: 165.774Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.214 0.239
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Ser/Thr protein phosphatases in fungi: structure, regulation and function.
Ariño et al. (2019)
1 more