Solution NMR

Solution structure of the LEDGF/p75 IBD - IWS1 (aa 446-548) complex


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
PC4 and SFRS1-interacting protein; Protein IWS1 homolog Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 23.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q96ST2 (Residues: 447-548; Coverage: 13%)
  • Canonical: O75475 (Residues: 345-442; Coverage: 19%)
Gene names: DFS70, IWS1, IWS1L, LEDGF, PSIP1, PSIP2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: simulated annealing
Chemical shifts: BMR34182  
Expression system: Escherichia coli