X-ray diffraction
1.99Å resolution

Tryptophan Repressor TrpR from E.coli wildtype with Indole-3-acetic acid as ligand

Source organism: Escherichia coli
Entry authors: Stiel AC, Shanmugaratnam S, Herud-Sikimic O, Juergens G, Hocker B

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Trp operon repressor Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 116 amino acids
Theoretical weight: 13.44 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P0A881 (Residues: 1-108; Coverage: 100%)
Gene names: JW4356, b4393, rtrY, trpR
Sequence domains: Trp repressor protein
Structure domains: TrpR-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P43
Unit cell:
a: 81.31Å b: 81.31Å c: 72Å
α: 90° β: 90° γ: 90°
R R work R free
0.197 0.194 0.243
Expression system: Escherichia coli BL21(DE3)