6eie

X-ray diffraction
2.72Å resolution

Ras guanine nucleotide exchange factor SOS2 (Rem-cdc25), with surface mutations

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Son of sevenless homolog 2 Chain: A
Molecule details ›
Chain: A
Length: 490 amino acids
Theoretical weight: 57.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07890 (Residues: 562-1047; Coverage: 37%)
Gene name: SOS2
Sequence domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, DESY BEAMLINE P11
Spacegroup: P43
Unit cell:
a: 53.97Å b: 53.97Å c: 183.793Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.218 0.285
Expression system: Escherichia coli