› 6edx

X-ray diffraction
2.01Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188382 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase Sgk3 Chain: A
Molecule details ›
Chain: A
Length: 118 amino acids
Theoretical weight: 14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96BR1 (Residues: 10-125; Coverage: 23%)
Gene names: CISK, SGK3, SGKL
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: I4
Unit cell:
a: 74.339Å b: 74.339Å c: 51.963Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.187 0.213
Expression system: Escherichia coli

Quick links

Citations

26 review citations

Novel roles of phosphoinositides in signaling, lipid transport, and disease.
Hammond et al. (2020)
25 more

3 mentions without citation

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Chandra et al. (2019)
2 more