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ERAP2 bound to Aryl Sulfonamide Uncompetitive Inhibitor

Source organism: Homo sapiens
Biochemical function: metalloaminopeptidase activity
Biological process: peptide catabolic process
Cellular component: membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF11838
Domain description: ERAP1-like C-terminal domain
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
The deposited structure of PDB entry 6ea4 contains 2 copies of Pfam domain PF11838 (ERAP1-like C-terminal domain) in Endoplasmic reticulum aminopeptidase 2. Showing 1 copy in chain A.

PF01433
Domain description: Peptidase family M1 domain
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
The deposited structure of PDB entry 6ea4 contains 2 copies of Pfam domain PF01433 (Peptidase family M1 domain) in Endoplasmic reticulum aminopeptidase 2. Showing 1 copy in chain A.

PF17900
Domain description: Peptidase M1 N-terminal domain
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
The deposited structure of PDB entry 6ea4 contains 2 copies of Pfam domain PF17900 (Peptidase M1 N-terminal domain) in Endoplasmic reticulum aminopeptidase 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001930
Domain description: Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
IPR042097
Domain description: Aminopeptidase N-like , N-terminal domain superfamliy
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
IPR024571
Domain description: ERAP1-like C-terminal domain
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
IPR014782
Domain description: Peptidase M1, membrane alanine aminopeptidase
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
IPR027268
Domain description: Peptidase M4/M1, CTD superfamily
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
IPR034016
Domain description: Aminopeptidase N-type
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2
IPR045357
Domain description: Aminopeptidase N-like , N-terminal domain
Occurring in:
  1. Endoplasmic reticulum aminopeptidase 2

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