6e5s

X-ray diffraction
2.06Å resolution

Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 2 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 133 amino acids
Theoretical weight: 15.61 KDa
Source organism: Homo sapiens
Expression system: Bacterial expression vector pBEN1-SGC
UniProt:
  • Canonical: P50120 (Residues: 2-134; Coverage: 99%)
Gene names: CRBP2, RBP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P212121
Unit cell:
a: 66.199Å b: 73.792Å c: 353.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.222 0.274
Expression system: Bacterial expression vector pBEN1-SGC