6dmo

Electron Microscopy
4.1Å resolution

Cryo-EM structure of human Ptch1 with three mutations L282Q/T500F/P504L

Released:
Source organism: Homo sapiens
Related structures: EMD-7964

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-171795 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Protein patched homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 1349 amino acids
Theoretical weight: 150.27 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q13635 (Residues: 1-1305; Coverage: 90%)
Gene names: PTCH, PTCH1
Sequence domains: Patched family

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.1Å
Relevant EMDB volumes: EMD-7964
Expression system: Homo sapiens