› 6djq

X-ray diffraction
3.1Å resolution

Vps1 GTPase-BSE fusion complexed with GDP.AlF4-

Released:
DOI: 10.2210/pdb6djq/pdb
PDB entry 6djq coloured by chain, front view.
PDB entry 6djq coloured by chain, side view.
PDB entry 6djq coloured by chain, top view.
Source organism: Thermochaetoides thermophila DSM 1495
Primary publication:
Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.
Varlakhanova NV, Alvarez FJD, Brady TM, Tornabene BA, Hosford CJ, Chappie JS, Zhang P, Ford MGJ
J Cell Biol 217 3608-3624 (2018)
PMID: 30087125

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124102 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative sorting protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 391 amino acids
Theoretical weight: 43 KDa
Source organism: Thermochaetoides thermophila DSM 1495
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: G0SFF0 (Residues: 1-354, 364-698; Coverage: 55%)
Gene name: CTHT_0061810
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand GDP 4 x GDP
Ligand ALF 4 x ALF
Ligand MG 4 x MG
Ligand NA 4 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 69.06Å b: 121.22Å c: 104.56Å
α: 90° β: 90.6° γ: 90°
R-values:
R R work R free
0.225 0.222 0.278
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

The structural biology of the dynamin-related proteins: New insights into a diverse, multitalented family.
Ford et al. (2019)
1 more

2 mentions without citation

Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.
Varlakhanova et al. (2018)
1 more